Role of Iron for Life and Iron Deficiency Across the Globe

Role of Iron for Life and Iron Deficiency Across the Globe

Iron has an important role in plants, animals, and microbes for electron transfer, oxygen transport, and storage, hormone synthesis, DNA replication, substrate oxidation-reduction, nitrogen fixation, repairing cell cycle control, and protection from reactive oxygen species (ROS) (Hurrell and Kelishadi, 2010). Iron deficiency is greatly affecting people all over the globe and must be eliminated by the right approaches to reduce health disorders and food insecure conditions.

It has a role in electron transfer, oxygen transport, and storage, hormone synthesis, DNA replication, substrate oxidation-reduction, nitrogen fixation, and repairing cell cycle control. Iron deficiency can impact all of these processes and lead to health problems.

Role of Iron for Human Body 

During chlorophyll biosynthesis, Fe acts as a catalyst and oxygen carrier. Its translocation within the plant parts is not much effective. Due to unique physiochemical properties, Fe takes part in redox reactions in the body. And also acts as a cofactor in various enzymatic reactions (Kim and Geurinot, 2007).

People Prone to Iron Deficiency

A greater proportion of the world population is suffering from micronutrient deficiencies. Among these nutritional disorders, Fe deficiency is the most widespread causing nutritional disorder across the world and it seriously affects human health, productivity, and life span. According to WGO estimates, 52% of pregnant women and 48% of children in developing countries are anemic (Akhtar et al., 2013).

Iron Requirements During Pregnancy 

During pregnancy, Fe intake requirements are increased by three folds due to the development of fetal placement growth and red cell mass (Pavord et al., 2012). Integrated effective management for the optimum supply of Fe to crop plants is the only possible sustainable strategy to reduce Fe deficiency in human beings.

Only by the biofortification of common beans, the extent of Fe deficiency can be reduced by 9-33% in northern Brazil (Darnton, 1999).

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Role of Iron for Agriculture and Crop Production

Nutritional contents and agricultural productivity is severely reduced by Fe deficiency (Zuo and Zhang, 2010).

Fe deficiency is often seen in calcareous, alkaline, and well-aerated soils (Schmidt, 1999).

Fe is acquired by the plants in two strategies (Puig et al., 2007).

Strategy I

These reactions take place in the plasma membrane of root epidermal cells encoded by the members of the ferric reductase oxidase (FRO) gene family (Wu et al., 2005; Mukherjee et al., 2006).

Strategy II

Strategy II is employed by the grasses and cereals. Phytosiderophores are released into the rhizosphere for chelation. There Fe3+ phytosiderophores complex is taken up by the root cells (Ishimaru et al., 2006).  Phytosiderophores chemistry is specie specific and it greatly determines the ability of grasses and cereals to acquire Fe from soil (Bashir et al., 2006).

Iron-Rich Dietary Sources 

Sustainable food-based approaches utilizing Fe-rich dietary sources in adequate amounts can be much effective for controlling Fe deficiency and other associated nutritional disorders. So different approaches should be developed for increasing Fe contents in edible plant tissues to reduce iron deficiency (Saini et al., 2016).

Biofortification vs GMO is a hot debate but biofortification is essentially important to improve Fe levels in the foods. It is sustainable and easy to implement an approach for poor communities.

Supplementation, vitamin D supplementation, vitamin-mineral supplementation, calcium supplementation, magnesium supplementation, vitamin D and calcium supplementation, B6 supplementation, and essential fatty acid. A supplementation is also a good approach but it is not affordable. For all people belonging to different regions and community standards.

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Iron deficiency is the most common nutrient deficiency in the world. It is estimated that 2 billion people, or 30% of the world’s population, are affected by it. Iron deficiency can result in anemia, which is a condition where there are not enough red blood cells to carry adequate oxygen to the body’s tissues. This can lead to fatigue, weakness, dizziness, and other symptoms. Those who have gastrointestinal disorders that impair nutrient absorption, and those who consume a vegetarian or vegan diet.

There are many ways to treat and prevent iron deficiency. Treatment may include taking an iron supplement, eating foods that are high in iron, or receiving an iron infusion. Prevention may include taking a vitamin C supplement with meals, eating foods that are high in vitamin C, and consuming plenty of fluids.

Iron is an essential mineral for life and Iron deficiency is a common problem across the globe. It can cause health problems such as fatigue, weakness, dizziness, and anemia. However, there are many ways to treat and prevent iron deficiency. Iron is found in many foods and can be supplemented or received through an infusion. Prevention includes eating foods that are high in vitamin C and drinking plenty of fluids. So make sure you’re getting enough Iron for a healthy life!


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